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A comprehensive review on mechanism of natural products against?Staphylococcus aureus
來源:食品科學(xué)網(wǎng) 閱讀量: 639 發(fā)表時間: 2022-05-30
作者: Yingying Zhao, Jinfeng Wei, Changqin Li, Adel F. Ahmed, Zhenhua Liu, Changyang Ma
關(guān)鍵詞: Natural products; Staphylococcus aureus; Antibacterial mechanism; Enzymes; Cell wall
摘要:

The abuse of antibiotics seriously threatens the therapeutic effect. Natural products from plants,?antimicrobial peptides?and micro-organisms have?antibacterial activity?against?Staphylococcus aureus. The mechanism of natural products reported in recent years on?S. aureus?includes six types, which are the acting on?bacterial cell wall, cytomembrane, metabolic pathway, protein, nucleic acid, biofilm and?quorum sensing?system to achieve antibacterial effect. This article summarized the mechanism of natural products reported in recent years on?S. aureus. It is found that the natural products acting on cell wall or cell wall synthesis pathway key enzymes are relatively safe and highly selective. It has the prospect of developing into medicine and provides the clue to investigate and utilize natural products in antibacterial activity.

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