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—— 中國食品雜志社
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Antiviral effect of polyphenol rich plant extracts on herpes simplex virus type 1
來源:食品科學(xué)網(wǎng) 閱讀量: 523 發(fā)表時(shí)間: 2019-09-24
作者: Sayed A. El-Toumya, Josline Y. Salib a,?, Walaa A. El-Kashak b, Christel Marty c, Gilles Bedouxc, Nathalie Bourgougnon c
關(guān)鍵詞: Egyptian plants; Anti-HSV-1; Polyphenols; Vero cell
摘要:

Evaluation of the anti-herpetic activity of 25 Egyptian plants extracts was investigated in vitro in this study. The antiviral activity against Herpes SimplexVirus type 1 (HSV-1)was done onVero cell lines by cell viability. Only two plants extracts; namely Euphorbia coopire (Euphorbiaceae) and Morus alba (Moraceae) showed potent anti-herpetic activity and six other extracts showed moderate inhibition. In contrast, a bioassay monitored phytochemical exploration of these two plants led to the isolation of pure flavonoid compounds. The antiviral activity of the isolated compoundswas also examined, among which seven pure compounds namely; 7-galloyl catechin, gallic acid, kaempferol 3-O- -(6 -O-galloyl)-glucopyranoside, quercetin 3-O- -(6 -O-galloyl)-glucopyranoside, curcumin, quercetin and kaempferol exhibited significant inhibition.

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